Abstract: AIM: To study the susceptibility of ure-aplasma urea1yticum (UU) to 7 antimicrobial agents.METHODS: A specific agent kit was used for UU cul-ture and drug susceptibility detection in vitro.RESULTS: 7 antimicrobial agents on the susceptibility of ureaplasma urea1yticum from high tolow were josamycin (96.67 %), doxycycline (90.67 %), minocyclin (88.67 %), shiba-floxacin (58.67 %), roxithromycin (39.33 %), ofloxacin (18.00 %), and azithromycin (8.00 %), respectively.The higher rates of drug resis-tance of UU were ofloxacin (31.33 %), shibafloxacin (18.67 %), and roxithromycin (18.00 %), respective-ly.CONCLUSION: UU shows multiple drug resistance. The determination of the susceptibility of UU to antimicro-bial agents can instruct reasonable medication and prevent the occurrence of drug resistance.

Key words: ureaplasma urea1yticum, drug suscepti-bility, antibiotic agents