Abstract: AIM: To observe the efficacy of hemoperfusion ( HP) to treat one case suffering from overdose digoxin poisoning. METHODS: HA 330 ml and YT-160 hemoperfusion cartridges were used and blood vessel was femoral vein, single needle and two-chamber catheter. Four HP were done. RESULTS: The blood digoxin level were 16 μg·L^-1 before and after the 1st HP, 9. 22 μg· L^-1 at the 2nd, 12. 4 μg·L^-1 before the 3th, 10. 45 μg· L^-1after the 3th, 3. 22 μg ·L ^-1before the 4th, and 2. 84 μg·L^-1 after the 4th HP. CONCLUSION: This case demonstrats that multiple HP at different period may decrease the blood digoxin level step by step.

Key words: digoxin, hemoperfusion, poisoning