Abstract: AIM: To evaluate the effects of radiotherapy combined IL-2 in the treatment of the transferred remnant of nasopharyngeal carcinoma in jugular lymph. METHODS: Treatment group ( n =32) was given radiation DA 6000-6800 cGy combined an injection of IL-2 4 ( 104 u ( three times each week). A routine radiation DA 6000-6800 cGy was adopted as a control group in another 31 cases. RESULTS: Lymph disappearance rate at treatment and control group reached 93. 8 % and 71. 0 %, respectively ( P < 0. 05); jugular humorless rate was 66. 7 % and 33. 3 %, respectively ( P <0. 05). The survival rates of 1, 2 and 3 year ( s) reached 73. 8 %, 59. 5 % and 42. 9 % in the treatment group, and 51. 2 %, 36. 6 % and 22. 0 % in the control group, respectively ( P <0. 05). The adverse actions did not show obvious difference between two groups. CONCLUSION: Incremental radiation combined partial injection of IL-2 is an effective remedy in the treatment of the transferred remnant of nasopharyngeal carcinoma in jugular lymph.

Key words: nasopharyngeal carcinoma, radiotherapy, immunotherapy, lymph