Abstract: AIM: To explore the therapeutic effects of flunarizine combined with aspirin in the treatment of migrainous cerebral infaction. METHODS: 38 cases of patients diagnosed as migrainous cerebral infaction were respectively given flunarizine 10 mg combined with aspirin 100 mg every night for a month.The observed indices included the dysfunction scores of nervous system, the total classes of living ability, and the accumulating rate of platelet and viscosity of plasma before and after the treatment. RESULTS: Before the treatment the dysfunction scores of nervous system and the living ability of the patients were 13.51 ±4.78 and 3.45 ±1.13, and after the treatment the values were 4.34 ±1.85 and 1.79 ±0.72 respectively (P <0.01).The accumulating rate of platelet and viscosity of plasma were 57.1 ±19.8 and 1.72 ±0.11 before the treatment, and the values were 35.12 ±7.94 and 1.70 ±0.11 respectively (P <0.01) after the treatment. CONCLUSION: Flunarizine combined with apirin shows a significant therapeutic effect in treatment of migrainous cerebral infaction.

Key words: migrainous headache, cerebral infarction, calaium channel block, flunarizine, aspirin