Abstract: AIM: To observe the clinical effects of daniston danshentong capsule in treatment of patients with nodular-cystic acne. METHODS: A group of patients (31 cases finished their observation in all 35 cases) was selected to take daniston danshentong capsule (0.25 g/capsule), 4 capsules three times daily.After continuous taking the agent for 8 weeks, the dosage changed to be 3 capsules three times daily.The treatment lasted for 12 weeks. RESULTS: The total effective rate was 83.9 %. Compared the mean number of the nodular-cystic acne before treatment (23 ±11) with that after 2 weeks of treatment (19 ±9), after 4 weeks (15 ±6), after 8 weeks (9 ±6), and after 12 weeks (7 ±7), all of the P values were less than 0.01.The effective rate increased gradually along with administration time lengthening. CONCLUSION: Daniston danshentong capsule is effective in treatment of nodular-cystic acne, and eight-week course is a suitable for the treatment.

Key words: pharmacodynamics, daniston danshentong capsule, acne, clinical assessment