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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2003, Vol. 8 ›› Issue (4): 370-373.

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Advances in study of new antiapoptosis factor :survivin

CHEN Yan-Ping, BI Fu-Yong   

  1. Department of Biochemistry,Wannan Medical College,Wuhu 241001,Anhui,China
  • Received:2003-03-10 Revised:2003-03-18 Online:2003-08-26 Published:2020-11-19

Abstract: Survivin has been identified recently as a unique member of the inhibitor of apoptosisProtein family.It is expressed during fetal development and in all common human cancers,but not in normal tissues.It can inhibit apoptosis induced by a variety of factors andPlay an important role during angiogenesis.Being a universal tumor-specific antiapoptosis inhibitor,survivin may serve as aPotential target for gene-protein-based therapy of tumor.

Key words: review, survivin, tumor, apoptosis, angiogenesis

CLC Number: