Abstract: AIM: To observe the anaesthesia of propofol and fentanyl used together by intravenous administration in induced abortion.METHODS: 140 women in early pregnancy (6-12 weeks) were allocated into observed group, in which all the women were injected by fentanyl (0.05-0.1 mg or 1.0-2.0 μg·kg ^-1) intravenously before operation and then by propofol (2 mg·kg ^-1) intravenously to provide anesthesic effect; then they were injected by bolus of propofol (0.5 mg·kg ^-1).during the operation.Another group with early pregnant women without any anesthetic as controlled group.The following indices were observed and compared between two groups, including pain feeling, the dilatation degree of cervical os, operation time and the in cidence of induced abortion syndrome as well as the bleeding volume, blood pressure (BP), heart rate (HR) and the blood oxygen saturation (SpO₂) before, during and after the operation.RESULTS: The pain feeling of the observed group was much less than that of the controlled group (P <0.01);the dilatation degree of the cervical os of the observed group was greater than that of the controlled group (P <0.01), the operation time was apparently shorter than that of the controlled group, and the incidence of abortion syndrome of the propofol-fentanyl group was less than that of the controlled group (P < 0.01).There were no differences in BP,HR and SpO₂ in observed group before and after the operation.There were no diffenences in bleeding volume between two groups. CONCLUSION: Propofol and fentanyl used together during the induced abortion operation can not only decrease the pain feeling, shorten the operation time and reduce the incidence of abortion syndrome signficantly, but also is safe, effective and economical, which is worth being applied further in clinic.

Key words: induced abortion, propofol, fentanyl, anesthesia, intravenous