Abstract: The objectivity of researchers is an essential value in scientific research and the basis for public trust.Conflict of interest refers to a conflict between an individual's private or personal interest and his or her duty, which could unduly influence one's position in fulfilling his or her duty.Conflicts of interest in clinical trial mainly consist of the conflicts of interest for investigators, for IRB members, for guardians of the subjects and those related with publishing scientific work.Strategies for dealing with conflicts of interest include disclosure, review, limiting and ethic training, etc.

Key words: medical ethic, clinical research, institutional review board, ethic review, conflicts of interest