Proliferation of vascular smooth muscle cells in cardiovascular diseases and drug research and development

Abstract

Abstract: The proliferation of vascular smooth muscle cells plays an important role in the initiation and aggravation in cardiovascular diseases such as hypertension, arteriosclerosis, restenosis.This article reviewed the progress in the studies on extracellular influencing factors, intracellular signal transduction, cell cycle of vascular smooth muscle cells and the relative drug research and development.

Key words: vascular smooth muscle cell, proliferation, signal transduction, cell cycle, drug research and Development

CLC Number:

R364.31

MA Bing-Liang, WU Yu-Lin. Proliferation of vascular smooth muscle cells in cardiovascular diseases and drug research and development[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2004, 9(8): 845-850.

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