Welcome to Chinese Journal of Clinical Pharmacology and Therapeutics,Today is Chinese

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2006, Vol. 11 ›› Issue (10): 1087-1091.

Previous Articles     Next Articles

Recent advances in study of endothelium-dependent hyperpolarizing factor

FAN Yi-fei, KONG De-hu, CHEN Zhi-wu, GAO Shan1   

  1. Department of Physidogy ;
    1Department of Pharmaology , Anhui Medical University , Hefei 230032 , Anhui , China
  • Received:2006-05-11 Revised:2006-06-23 Online:2006-10-26 Published:2020-11-05

Abstract: Besides cyclooxygenase and nitric oxide synthase, another distinct endothelial pathway, endothelium-dependent hyperpolarization factor (EDHF) , is involved in relaxation of the vascular smooth muscle cells.EDHF has been demonstrated unequivocally in various blood vessels from different species, including human,and is likely to play an important role in cardiovascular physiology and pharmacology.

Key words: endothelium-dependent hyperpolarization factor, vasodilatation, potassium channels

CLC Number: