Effects of extract of Sonchus oleraceus on cardiovascular protection

Abstract

Abstract: AIM: To observe the cardiovascular protective effects of extract from Sonchus oleraceus. METHODS: Several experiments including hypoxia experiment, the survival test of hungry mice, acute myocardial ischemia, and electrical stimulation of thrombosis model in rats were used to evaluate the pharmacy activity of extract of Sonchus oleraceus. RESULTS: Extract of Sonchus oleraceus markedly prolonged the living time of the fasting, hypoxia experimetal mice, the formation time of carotid artery thrombosis, decreased blood viscosity shear rate (compared with control, P < 0.01), prevent myocardial ischemia caused by hypophysin. CONCLUSION: Extract of Sonchus oleraceus can prolong formation time of carotid artery thrombosis, anti-myocardial ischemia and then protect cardiovascular.

Key words: extract of Sonchus oleraceus, blood viscosity, carotid artery thrombosis, myocardial ischemia, living time

CLC Number:

R965.2

MU Yan-ling, XIE Yan-ying, ZHOU Ling, XU Shu-lan, HU Zhi-li, WANG Fu-wen. Effects of extract of Sonchus oleraceus on cardiovascular protection[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(12): 1241-1320.

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Effects of extract of Sonchus oleraceus on cardiovascular protection

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