Abstract: AIM: To clarify the healing effect of Shuanghuanglian liquor on the wounded surface of the scalded or burnt rats. METHODS: We made rats’scalded or burnt models on backs or feet, respectively. Those rats were divided into three groups :the model group, the sulfadiazine silver treated group and the Shuanghuanglian liquor treated group, in order to observe the healing process of the wounded surface in the three experimental groups. RESULTS : The cold and wet application of Shuanghuanglian liquor could not only shorten the time for the healing of the wounded surface of scalded or burnt rats, but also reduce the size of the wound. The healing rate of Shuanghuanglian liquor was similar to that of sulfadiazine silver group, but was much higher than that of the modeled group. Under the microscope, we observed that the skin appendages in dermis were still in integrity. No edema or inflammatory cell infiltration was found. CONCLUSION: The cold and wet application of Shuanghuanglian liquor shortens the healing course of wounded skin in scald or burnt rats.

Key words: Shuanghuanglian liquor, scald, burn, healing of the wounded surface