Initial study on anticancer effect of serum thymic factor

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2007, Vol. 12 ›› Issue (6): 668-671.

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Initial study on anticancer effect of serum thymic factor

ZHANG Chang-ping¹, LE Jia-jing², LI Zhan-jun², XU Kang-sen²

¹Nanjing Medical University, Nanjing 210029, Jiangsu, China;
²National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China

Received:2007-03-10 Revised:2007-05-16 Published:2020-11-09

Abstract

Abstract: AIM:To study the inhibitory effect of serum thymic factor (FTS) on cancer cells.METHODS: Bearing cancer mice, rats were administrated with different dosages of FTS. Life extension rate and inhibitory rate were determined. Stimulation index (SI) and delayed hypersensitivity were observed, too.RESULTS:Life extension rate or inhibitory rate in mice exceeded 30% in 0. 25 mg/kg group and 0.13 mg/kg group, and those parameters in rats also exceeded 30% in FTS three groups. After Con-A stimulation, SI achieved maximum at 0. 016 mg/mL.Delayed hypersensitivity also showed positive results.CONCLUSION:FTS has significant inhibitory effect on the growth of EAC, H22 and W256 cancer cells.

Key words: serum thymic factor, inhibitory rate, life extension rate, immunological enhancement

CLC Number:

R965. 2

ZHANG Chang-ping, LE Jia-jing, LI Zhan-jun, XU Kang-sen. Initial study on anticancer effect of serum thymic factor[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2007, 12(6): 668-671.

References

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Initial study on anticancer effect of serum thymic factor

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