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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2007, Vol. 12 ›› Issue (7): 735-738.

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Function of melatonin in human retina

HUANG Wen-li, TANG Min, FAN Ying   

  1. Affiliated First People's Hospital of Shanghai Jiaotong University, Shanghai 200080, China
  • Received:2007-02-01 Revised:2007-04-01 Online:2007-07-26 Published:2020-10-27

Abstract: Melatonin(MLT) is an indolakylamine with many physiological functions, and retina is one of its natural secretory portions.Melatonin plays an important role in retina, including regulating diurnal rhythmicity of retina, protecting against oxidation and apoptosis, regulating retinal neural network and so on.Researches on mechanism of action may appreciate ophthalmological clinical application of melatonin.So this article will review on its synthesis, metabolism, acceptors distribution and function in retina.

Key words: melatonin, retina, diurnal rhythmicity, antioxidant, neural network

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