Abstract: AIM: To evaluate the clinical efficacy and safety of ornidazole vaginal effervescent tablets in the treatment of bacterial vaginitis. METHODS: A random, double blind and parallel control trial method was adopted .132 patients with bacterial vaginitis were randomly assigned into trial group ( 67 cases) or control group ( 65 cases) .And patients received ornidazole vaginal effervescent tablets or metronidazole vaginal ef-fervescent tablets once daily for 7 days. Therapeutic effect of two groups were observed in 3-7 days and 28-35 days after treatment .RESULTS: The clinical cure rate, efficacy rate in 3-7 days and 28-35 days after the treatment were 88.52 %, 95.08%, 93.44%, 96.43% respectively, while those for control group were 78.69%, 91 .80%, 85.25%, 90.17%respec-tively .Adverse effect occurrence rate of trial group and control group were 1.5% and 4.9% respectively . There were no significant differences between the two groups( P >0.05) .CONCLUSION: Ornidazole vagi-nal effervescent tablets is a safe and effective agent for the treatment of bacterial vaginitis.

Key words: bacterial vaginitis, ornidazole vaginal effervescent tablets, clinical study