Abstract: AIM: To evaluate the efficacy of levocarnitine in treating patients with acute exacerbation of chronic pulmonary heart disease. METHODS: 126 patients were divided into two groups randomly: 60 patients in control group were treated with conventional therapy for inhalling oxygen, controlling infection, relieving asthma, expelling phlegm and diuresis ;66 patients in test group were treated with 3 g /d levocarnitine, i.v. drip for 14 days in addition to conventional therapy. RESULTS: The total effective rate in test group was superior to that of control group(P <0.01). The arterial blood gases, cardiac index, ejection fraction and right ventricular internal diameter were improved significantly(P <0.01) in two groups. The test group was remarkably improved compared with control group after treatment (P <0.01). CONCLUSION: Levocarnitine is effective in treating patients with acute exacerbation of chronic pulmonary heart disease.

Key words: levocarnitine, pulmonary heart disease, acute exacerbation