Experimental study on therapeutic effects of quercetin on abacterial prostatitis

Abstract

Abstract: AIM: To study the anti-inflammatory effects of quercetin on the experimental animal models of abacterial prostatitis.METHODS: Five types of experimental animal inflammatory models in vivo were applied to investigate the anti-inflammatory and analgesic effects of quercetin, including xiaozhiling-induced chronic prostatitis, carrageenan-induced acute prostatitis, croton oil-induced auricle swelling, photothermal stimulation-induced pain, cotton ball granuloma test of mice, and the rabbit urethral smooth muscle tensile test in vitro to examine the catabatic effects on dysuria.RESULTS: Quercetin displayed good anti-inflammatory effects on acute and chronic abacterial prostatitis. Quercetin also had good inhibitory effects on croton oilinduced auricle swelling, photothermal stimulation-induced pain and cotton ball granuloma test of mice and had definite relaxing effects on rabbit urethral smooth muscle.CONCLUSION: It indicates that quercetin has good therapeutic effects on abacterial prostatitis and could alleviate dysuria.

Key words: quercetin, prostatitis, therapeutic

CLC Number:

R965.2

CHENG Li-yan, ZHENG Xiao-liang, SHI Hong. Experimental study on therapeutic effects of quercetin on abacterial prostatitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(6): 648-653.

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