Development of therapeutic biologics in cancer treatment

doi:10.12092/j.issn.1009-2501.2020.01.005

Abstract

Abstract: Cancer treatment is always the focus of pharmaceutical development while therapeutic biologics play an important role alongside. This review is focused on the development of therapeutic biologics in cancer treatment and categorized by targeted therapy and immunotherapy by mechanism. In targeted therapy, monoclonal antibodies, biosimilars and antibody-drug conjugates are discussed in details, while for immunotherapy, checkpoint inhibitors, T-cell transfer therapy and bispecific antibody are introduced, respectively.

Key words: therapeutic biologics, cancer treatment, targeted therapy, immunotherapy

CLC Number:

ZHANG Kaiting, CHEN Naihan. Development of therapeutic biologics in cancer treatment[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, doi: 10.12092/j.issn.1009-2501.2020.01.005.

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