Effects of Ginkgo biloba extracts on CYP450

Abstract

Abstract: Ginkgo biloba extract (GBE) is a popular herbal medicine and has received great attention in clinical therapy.Interactions between GBE and other drugs are of increasing concern.Among these interaction, induction and inhibition of hepatic drug metabolizing enzymes by GBE have been investigated. This review focuses mainly on research about the effects of GBE on CYP450:CYP3A4, CYP2C9, CYP1A2, CYP2C19.

Key words: Ginkgobilobaextracts, CYP3A4, CYP2C9, CYP1A2, CYP2C19

CLC Number:

R969

TAO Gong-you, ZHOU Hong-hao. Effects of Ginkgo biloba extracts on CYP450[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(9): 1071-1075.

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