Abstract: AIM: To examine the rational use of antibiotics in acute pancreatitis of Xi-Jing hospital. METHODS: Retrospective analysis 93 patients who were provided with antibiotics drugs of acute pancreatitis patients from January to December of 2008. RESULTS: There are 93 AP cases in the DegestionMedical Department.78 MAP cases account for 83.67 %, 15 SAP cases account for 16.13 %.Excessus-medication were found in prophylaxis utilization in antibacterials drug, for the bulk of antibacterials drug combination was unreasonable, the reasonable course of treatment only account for 30 %.The rates of bacterial culture were too low in infection cases, which caused severity experience medication. CONCLUSION: Generally, the choices of antibiotic are rational, but there are still substandard usage of antibiotics in hospital, and it's necessary to improve the management of rational usage of antibiotics.

Key words: acute pancreatitis, antibacterials, rational usage of antibiotics