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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2010, Vol. 15 ›› Issue (3): 356-360.

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Progress of Hemodilution on the role of muscle relaxant effects

YUAN Xiao-hong1, GUO Jian-rong1, JIN Xiao-ju2   

  1. 1Department of Anesthesiology, Lihuili Hospital, Medical School of Ningbo University,Ningbo 315040,Zhejiang,China;
    2Department of Anesthesiology,Yijishan Hospital of Wannan Medical College, Wuhu 241001,Anhui,China
  • Received:2010-02-20 Revised:2010-03-16 Published:2020-10-14

Abstract: Hemodilution (HD) is a commonly blood conservation method that used to reduce autologous blood loss and allogeneic blood transfusion during operation,but it often causes changes of hemodynamics,blood components and internal environment,resulting in anesthetic drugs appearing some impact of pharmacodynamics and pharmacokinetics,especially muscle relaxants.In this article,the progress of hemodilution on the role of muscle relaxants effects is reviewed.

Key words: Hemodilution, Muscle relaxants, Pharmacokinetics, Pharmacodynamics

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