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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2010, Vol. 15 ›› Issue (4): 438-442.

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Software design for data analysis of individual antihypertensive drugs therapy related genotyping microarray

HUANG Yuan-fei1,2, PENG Jian3, ZHAO Zhen-yu2, YANG Hong2, XIAO Peng2, TANG Jing-bo1, SHEN Jie2,4, ZHANG Yang-de1   

  1. 1National Hepatobiliary & Enteric Surgery Research Center, Central South University,
    2Institute of Clinical Pharmacology, Central South University,
    3National Hepatobiliary & Enteric surgery Research Center, Xiangya Hospital of Central South University, Changsha 410078, Hunan,China,
    4Anhui Provincial Center for Drug Clinical Evaluation, Wuhu 241001, Anhui, China
  • Received:2010-03-07 Revised:2010-04-10 Published:2020-09-17

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Abstract: AIM: Base on individual antihypertensive drugs therapy related genotyping microarray, with platform of Microsoft Visual Basic 6.0, developed hypertension microarray data analysis system v1.0. By reading GPR or LSR file produced by microarray scanners, the system automatic determine microarray validity, generate relative genetype result and store for later database manage. METHODS: The Microsoft Visual Basic V6.0 was used for programming tools. RESULTS: After analysised 1025 microarray, the results showed that system run smoothly and reliable, greatly increased the analysis efficiency. CONCLUSION: Software design succeed, achieved the desired objectives.

Key words: Hypertension, Microarray, Gene chip, Visual basic v6.0, Individual medication, SNP

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