Abstract: AIM: To investigate the protective effects of Phytosterols on abacterial prostatitis in rats.METHODS: Experimental abacterial prostatitis induced by xiaozhiling and carrageenan respectively were used to observe the protective effects of Phytosterols. Auricle swelling induced by croton oil, granuloma induced by cotton ball and pain induced by photothermal stimulation in mice were used to detect the anti-inflammatory and analgesic effects of Phytosterols. Water-loaded rats were used to detect the diuresis effect of Phytosterols.RESULTS: In xiaozhiling-induced chronic abacterial prostatitis rats treated with 150 mg/kg of Phytosterols, the number of white blood cells in prostatic secretion was obviously decreased, and the density of lecithin corpuscle in prostatic secretion was obviously increased, and the edema, inflammatory infiltration and proliferation in prostate were partly recovered, as well as in carrageenan-induced acute abacterial prostatitis rats. The acute auricular swelling induced by croton oil, late proliferative granuloma induced by cotton ball and pain induced by photothermal stimulation in mice were attenuated by 150 mg/kg of Phytosterols. The urinary amount was significantly increased by 150 mg/kg of Phytosterols in water-loaded rats in 4 hours.CONCLUSION: These results demonstrate that Phytosterols have good protective effects on abacterial prostatitis.

Key words: Phytosterols, Abacterial prostatitis