Abstract: AIM: To observe the clinical effect of botulinum toxin type A combining rehabilitation for the treatment of children cerebral palsy.METHODS: Thirty-two cases of children cere bral palsy admitted to hospital from March 2009 to March 2011 were randomly divided into two groups, control group(n=16) and treatment group(n=16). The control group was given conventional rehabilitation training; the treatment group was also given injection of botulinum toxin A. The clinical effects in 2 groups were observed and compared.RESULTS: After treatment, the GMFM score in the treatment group was significantly higher than that in the control group (P<0.05). The Ashworth score in the treatment group was significantly lower than that in the control group (P<0.05); and the popliteal fossa angle, foot disaffection angle and abduction angle in the treatment group were superior to those in the control group(P<0.05).CONCLUSION: There is a significant clinical effect of botulinum toxin type A combining rehabilitation for the treatment of children cerebral palsy.

Key words: Cerebral palsy, Botulinum toxin type A, Rehabilitation training