Experimental study on pharmacodynamic of Liyan capsule on Chronic pharyngitis

Abstract

Abstract: AIM: To provide experimental basis for clinical therapy by studying the pharmacodynamic of Liyan capsule.METHODS: The effects of Liyan capsule on painkillers, anti-inflammatory and chronic inflammation were observed through animal model.RESULTS: Liyan capsule can reduce the writhing times of the mice induced by acetic acid(P<0.05),and inhibit the weight of granuloma induced by cotton ball and capillary permeability in mice(P<0.05).In the chronic pharyngitis model induced by ammonia water, Liyan capsule can increase the weight and reduce the body temperature of rabbits, it also can improve hyperplasia of chronic inflammatory cells,stagnant blood ,abscess in the mucosal epithelium(P<0.05).CONCLUSION: Liyan capsule has an action on analgesia, anti-inflammatory and has great curative effect on chronic pharyngitis

Key words: Liyan capsule, Chronic pharyngitis, Pharmacodynamic

CLC Number:

R965.2

ZHANG Dan-dan, SONG Ya-juan, WANG Xin, LI Yi-hang, ZHANG Shu-ming, WANG Wei-ming. Experimental study on pharmacodynamic of Liyan capsule on Chronic pharyngitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(3): 254-258.

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Experimental study on pharmacodynamic of Liyan capsule on Chronic pharyngitis

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