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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2011, Vol. 16 ›› Issue (7): 830-836.

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Advancement of the drug monitoring methods of immunodepressants in human blood

WANG Yan1, BU Wen-ting2, LI Peng-fei1, MA Ping1, GAO Wen-jing1, SUN Jian-zi1   

  1. 1Pharmacy Department of the Second Artillery General Hospital, Beijing 100088, China;
    2Institute of Population Research, Peking University, Beijing 100087,China
  • Received:2011-03-30 Revised:2011-06-24 Online:2011-07-26 Published:2011-09-22

Abstract: Immunodepressants are mainly applied to treat autoimmune diseases clinically and organ transplantation.Therapeutic drug monitoring is needed to use immunodepressants and clinicians usually adjust the dosage according to the detection results.This review summarizes the detection methods of immunodepressants in human blood, such as tacrolimus, ciclosporin, mycophenolate , glucocorticosteroid, sirolimus and everolimus.

Key words: Immunodepressants, Therapeutic drug monitoring, Organ transplantation

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