Structure and regulation of biological rhythms of olfactory bulb

Abstract

Abstract: Olfactory bulb is a key component of olfaction. Recent researches have found that olfactory bulb regulates the biological rhythms, and it expresses regulatory genes relatively independent of suprachiasmatic nucleus. Based on the research of the structure and regulation of biological rhythms of olfactory bulb, it has become a new focus in basic and clinical medicine to study some nervous system diseases and biological rhythms such as sleep. This article summarizes the structure and the effect on regulating biological rhythms of olfactory bulb.

Key words: Olfactory bulb, Structure, Biological rhythms

CLC Number:

R338

XU Xing-yuan, WANG Yi-qun. Structure and regulation of biological rhythms of olfactory bulb[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(8): 933-936.

References

[1] Song C, Leonard BE. The olfactory bulbectomised rat as a model of depression[J]. Neurosci Biohehav Rev, 2005, 29(4/5): 627-647.
[2] Stevenson RJ. An Initial evaluation of the functions of human olfaction[J]. Chem Senses, 2010, 35(1): 3-20.
[3] Whitman MV, Greer CA. Adult neurogenesis and the olfactory system[J]. Prog Neurobiol, 2009, 89(2): 162-175.
[4] Yusuke Tsuno, Kashiwadani H, Mori K. Behavioral state regulation of dendrodendritic synaptic inhibition in the olfactory bulb[J]. J Neurosci, 2008, 28(37): 9227-9238.
[5] Yamada K, Hasegawa M, Kametani S, et al. Nose-to-brain delivery of TS-002, prostaglandin D2 analogue[J]. J Drug Target, 2007, 15(1): 59-66.
[6] Kelly JP, Wrynn AS, Leonard BE. The olfactory bulbectomized rat as a model of depression: an update[J]. Pharmacol Ther, 1997, 74(3): 299-316.
[7] Wrynn AS, Mac Sweeney CP, Franconi F, et al. An in vivo magnetic resonance imaging study of the olfactory bulbectomized rat model of depression[J]. Brain Res, 2000, 879(1/2): 193-199.
[8] Shieh KR. Distribution of the rhythm-related genes rPERIOD1, rPERIOD2, and rCLOCK, in the rat brain[J]. Neuroscience, 2003, 118(3): 831-843.
[9] Hardy AB, Aïoun J, Baly C, et al. Orexin A modulates mitral cell activity in the rat olfactory bulb: patch-clamp study on slices and immunocytochemical localization of orexin receptors[J]. Endocrinol, 2005, 146(9): 4042-4053.
[10] Blakemore LJ, Levenson CW, Trombley PQ. Neuropeptide modulates excitatory synaptic transmission in the olfactory bulb[J]. Neuroscience, 2006, 138(2):663-674.
[11] Castro JB, Urban NN. Subthreshold glutamate release from mitral cell dendrites[J]. J Neurosci, 2009, 29(21): 7023-7030.
[12] Granados-Fuentes D, Saxena MT, Prolo LM, et al. Olfactory bulb neurons express functional, entrainable circadian rhythms[J]. Eur J Neurosci, 2004, 19(4): 898-906.
[13] Granados-Fuentes D, Prolo LM, Abraham U, et al. The suprachiasmatic nucleus entrains, but does not sustain, circadian rhythmicity in the olfactory bulb[J]. J Neurosci, 2004, 24(3): 615-619.
[14] Abraham U, Prior JL, Granados-Fuentes D, et al. Independent circadian oscillations of Period1 in specific brain areas in vivo and in vitro[J]. J Neurosci, 2005, 25(38): 8620-8626.
[15] Aston-Jones G, Chen S, Zhu Y, et al. A neural circuit for circadian regulation of arousal[J]. Nat. Neurosci, 2001, 4(7): 732-738.
[16] Bernabeu R, Thiriet N, Zwiller J, et al. Lesion of the lateral entorhinal cortex amplifies odor-induced expression of c-fos, junB, and zif 268 mRNA in rat brain[J]. Synapse, 2006, 59(3): 135-143.
[17] Funk D, Amir S. Circadian modulation of fos responses to odor of the red fox, a rodent predator, in the rat olfactory system[J]. Brain Res, 2000, 866(1/2): 262-267.
[18] Granados-Fuentes D, Tseng A, Herzoq ED. A circadian clock in the olfactory bulb controls olfactory responsivity[J]. J Neurosci, 2006, 26(47): 12219-12225.
[19] Le Magnen J. Increased food intake induced in rats by changes in the satiating sensory input from food [J]. Appetite, 1999, 33(1): 33-35.
[20] Abe M, Herzog ED, Yamazaki S, et al. Circadian rhythms in isolated brain regions[J]. J Neurosci, 2002, 22(1): 350-356.
[21] Hawkes CH, Del Tredici K, Braak H. Parkinson's disease: the dual hit theory revisited[J]. Ann N Y Acad Sci, 2009, 1170: 615-622.