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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2012, Vol. 17 ›› Issue (5): 573-581.

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Recent status and progress of chemotherapy treatment for metastatic non-small-cell lung cancer

QI Quan, ZHAO Wen-ying   

  1. Wannan Medical College, Wuhu 241000, Anhui,China
  • Received:2011-11-18 Revised:2012-05-03 Online:2012-05-26 Published:2012-05-28

Abstract: In recent years, smoking,pollution and lampblack lead to the morbidity and mortality of lung cancer rapid growth. Non-small-cell lung cancer onset occult, development is rapid, and the prognosis is poor. Most of the patients with newly diagnosed is transferred (IV stage) and lost the opportunity to surgery, chemotherapy is the main treatment method, which purpose is to prolonging the survival time and the quality of life. At present clinical application of chemotherapy is mainly platinum-based and the third generation cytotoxic drugs. The best treatment strategy which based on functional genomics and proteomics in individual therapy design for every patient with lung cancer is the direction of the clinical development and the ideal mode of treatment of the 2l century. This paper reviews the recent status and progress of chemotherapy treatment for metastatic non-small-cell lung cancer.

Key words: Metastatic non-small-cell lung cancer, Chemotherapy, Individualized treatment

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