Research progress on relationship between eNOS and ACE gene polymorphisms and coronary heart disease

Abstract

Abstract: Coronary heart disease (CHD) is one of the most serious disease that affects human health and life. It is also a public health problem concerned worldwide. The nitric oxide synthase (eNOS) and angiotensin-converting enzyme (ACE) have an important influence on the cardiovascular system in vivo. The genomics study found that the eNOS and ACE gene polymorphism correlate with the occurrence of CHD. This article covers the progress between eNOS and ACE gene polymorphism and coronary heart disease susceptibility.

Key words: Coronary heart disease, Endothelial nitric oxide synthase, Angiotensin converting enzyme, Gene polymorphism

CLC Number:

R968

FANG Chao, ZENG Hui, ZHOU Hong-Hao, LIU Zhao-Qian. Research progress on relationship between eNOS and ACE gene polymorphisms and coronary heart disease[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 18(2): 222-228.

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