Research development between JNK pathway and apoptosis

Abstract

Abstract: JNK pathway is closely associated with cell differentiation, apoptosis, stress response and many hunman diseases in the past 20 years, whose biochemical function, regulation under cell physiology and pathology are constantly noticed by domestic and foreign scholars. Recently, more research suggests that it plays an important role in regulating apoptosis, and it will be an important potential target for treatment of apoptosis-associated disease by regulating JNK signal pathway. In summary, the physiological and pathophysiological functions of JNK pathway and relation with apoptosis have been reviewed.

Key words: JNK pathway, Apoptosis, Mitogen activated protein kinase

CLC Number:

R965.2

WEI Na, HE Hai-bo, ZHANG Chang-cheng, YUAN Ding, WANG Ting. Research development between JNK pathway and apoptosis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 18(7): 807-812.

References

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