Advances in the study of Burkholderia cepacia complex

Abstract

Abstract: The Burkholderia cepacia complex(Bcc) is a group of nonfermenter aerobic gram-negative bactetia also an important opportunistic pathogens which easily causes infections in cystic fibrosis patients and chronic granulomatous disease. All of this result in patients asymptomatic carriage, chronic infection or cepacia syndrome. Besides CF and CG, cases infected of Burkholderia cepacia complex are growing because antimicrobial agents abuse, it induces pneumonia, blood poisoning, wound infected, deeping abscess and urinary tract infections. The advances in the study of the Burkholderia cepacia complex in genomovars, epidemiology characteristic identification approach,virulent factor and resistant mechanism are reviewed in this paper.

Key words: Burkholderia cepacia complex , Genomovars, Epidemiology characteristic, Identification approach, Virulent factor, Resistant mechanism

CLC Number:

R446.1

WANG Yu-ping, LI Xiao-ning, ZHANG Ying-ying. Advances in the study of Burkholderia cepacia complex[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(1): 101-104.

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