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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2014, Vol. 19 ›› Issue (10): 1177-1182.

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Advances in pharmacological research of 8-methoxypsoralen

YANG Jian1, YANG Qian2   

  1. 1 Department of Chemistry, Nanjing Normal University, Nanjing 210024,Jiangsu,China;
    2 Deptment of Pharmacology, Nanjing Medical University, Nanjing 210029,Jiangsu,China
  • Received:2013-05-24 Revised:2014-06-20 Online:2014-10-26 Published:2014-10-29

Abstract: 8-methoxypsoralen (8-MOP) is widely distributed in the roots or fruits of Chinese medicinal herb, such as fructus cnidii, radix glehniae, angelica daharica, fructus aurantii immaturus, notopterygium and coriander. This paper overviews the advances and applications of 8-MOP in the antimicrobial and inhibition of inflammation, the regulation of immune function, anti-tumor effect, other pharmacological effects and toxicological effects basing on our work and crosslinking current researches at home and abroad.

Key words: 8-methoxypsoralen (8-MOP), pharmacological effect, antitumor effect

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