Abstract: AIM: To analyze the concurrent bleeding-related causes and identify effective prevention measures of common bile duct stones by ERCP and EST. METHODS: 299 cases of common bile duct stones underwent ERCP and EST lithotomy clinical data of Digestive Endoscopic Center in Yijishan Hospital of Wannan Medical College from January 2012 to December 2012 were researched and analyzed. RESULTS: The 299 patients,52 cases of less bleeding and 50 cases of significant bleeding in surgery, the difference of the time inserting nipple by analysis of variance (F=3.713) was statistically significant (P=0.026); in the bleeding cases, 21 cases of diverticulum, the difference of the relationship between the amount of bleeding and diverticula by the chi-square test (χ² =5.314) was statistically significant (P<0.05); the Fisher exact test showed that hemostasis titanium clips under endoscopic was more efficient than electric coagulation therapy (P<0.05); in 11 cases of postoperative bleeding, 6 cases treated by drugs,4 cases were invalid, 4 cases treated by endoscopic hemostasis treatment, all cases were effective, the Fisher exact test showed that the postoperative bleeding under endoscopic was more efficient than therapy of drugs (P<0.05). CONCLUSION: The concurrent bleeding of common bile duct stones by ERCP and EST is related to the time of successfully inserting the nipple, and the exist of diverticulitis, endoscopic hemostasis treatment is the effective measure of preventing and treating bleeding.

Key words: ERCP, EST, bleeding, endoscopic