Clinical research of new type P2Y12 Receptor inhibitor ticagrelor

Abstract

Abstract: Antiplatelet drug is the cornerstone for CHD (coronary heart disease) treatment, which is beneficial to the myocardial ischemia prevention and treatment as well complication intervention. At present, the CHD (coronary heart disease) and PCI (percutaneous coronary intervention) treatment manual recommends to use oral antiplatelet drugs including clopidogrel, ticagrelor, trasugrel together with aspirin dual antiplatelet therapy for recurrent ischemic events prevention. This article introduces the pharmacokinetics and pharmacodynamics features of new type P2Y12 receptor inhibitor ticagrelor, as well as evidence-based medical evidence in patients with coronary artery disease.

Key words: acute coronary syndrome, ticagrelor, clopidogrel, antiplatelet, percutaneous coronary intervention

CLC Number:

R541.4

ZHANG Xia, KE Yong-sheng. Clinical research of new type P2Y12 Receptor inhibitor ticagrelor[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(4): 459-464.

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