Abstract: AIM: To study the clinical efficacy of Fuxin Decoction in the treatment of heart failure. METHODS: The 120 patients with heart failure in our hospital during the period from Feb 2013 to Dec 2013 were randomized into the control group (routine theraphy) and the observation group (based on the control group, addition to the Fuxin Decoction), 60 patients per group. The efficacy of heart function and TCM syndrome scores, adverse reactions, and the left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) and E/A value on pre- and post-treatment in the two groups were observed and compared. RESULTS:Compared with control group, the heart function efficacy (91.7% vs 78.3%) and TCM syndrome scores efficacy (91.7% vs 73.3%)were significantly increased, the incidence of adverse reactions was obviously reduced (5.0% vs 16.7%)in the observation group, P<0.05; compared with control group, the LVEF(47.0±1.0 vs 44.4±1.2)and E/A values (1.3±0.4 vs 1.0±0.3)were significantly increased on the post-treatment in the observation group, P<0.05. CONCLUSION: The efficacy of Fuxin Decoction in the treatment of heart failure is significant with high safety, improve the patient's heart function and prognosis quality, and is worthy of clinical promotion.

Key words: Fuxin Decoction, heart failure, efficacy