Abstract:

AIM: To analyze the surgical antimicrobial prophylaxis and to evaluate the effectiveness of different antimicrobial solutions about type I incision operation in a cancer hospital. METHODS: Three-hundred cases of clean surgery in our hospital from January to December in 2017 were involved and the data of the surgical antimicrobial prophylaxis were retrospective collected and evaluated.The cost-effectiveness analysis method was applied to compare the ratio of cost to effectiveness between the three solutions. RESULTS:The utilization ratio of antibiotics in clean surgery was 16.33%, which met the hospital requirements. Cefazolin (55.11%) and Cefuroxime (28.57%) were mainly preventive use in the 49 cases of antibiotics. DUI values of antibiotics for prophylaxis were ≤1, antibiotics dosage for single day was reasonable. The inappropriate use of antibiotics was mainly manifested in “unsuitable varieties”, which accounted for 63.64% of the total irrational rate. CONCLUSION: From the perspective of ecnnomic medication, the preoperative uses of cefazolin in patients treated with clean surgery was a better option.

Key words: type I incision operation, perioperative period, antibiotics, rational drug use, cost-effectiveness analysis