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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2020, Vol. 25 ›› Issue (1): 94-100.doi: 10.12092/j.issn.1009-2501.2020.01.014

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Correlation between vitamin D and thyroid disease

SU Shan 1,2, ZHANG Di 1,2, WANG Qiangmei 1,2, ZHEN Donghu 2   

  1. 1 The First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu, China; 2 Department of endocrinology, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China
  • Received:2019-10-28 Revised:2019-12-10 Online:2020-01-26 Published:2020-02-11

Abstract: In addition to the role of vitamin D in regulating calcium and phosphorus homeostasis and bone metabolism, immune regulation and anti-tumor proliferation have been gradually proposed by researchers. At present, a large number of studies have found that patients with thyroid diseases have low vitamin D levels, and it is believed that vitamin D insufficiency/ deficiency may be involved in the pathogenesis of thyroid diseases, but the specific relationship and mechanism between vitamin D and thyroid diseases have not been fully clarified. This article reviewed in the relationship between vitamin D and several common thyroid diseases in recent years, in order to analyze the role of vitamin D in the pathogenesis of thyroid diseases, as well as the influence of vitamin D supplementation on the occurrence and development of thyroid diseases.

Key words: vitamin D, Graves' disease, Hashimoto's thyroiditis, thyroid nodules, thyroid cancer

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