Mediation of P-selectin in myocardial ischemia-reperfusion injury

Abstract

Abstract: The process of myocardial ischemia-reperfusion injury (MI/RI) is complex and dynamic. Platelets,neutrophils and vascular endothelial cells are three key players in MI/RI, and P-selectin plays an important role in the transductive regulation among these players. This review summarizes the mediationof P-selectin among several kinds of materiaes in the process of MI/RI.

Key words: P-selectin, Myocardial ischemia-reperfusion injury, Platelets, Neutrophils, Vascular endothelial cells

CLC Number:

JIN Kang, KAN Hong-wei. Mediation of P-selectin in myocardial ischemia-reperfusion injury[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(2): 238-240.

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