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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2009, Vol. 14 ›› Issue (7): 827-832.

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Cell co-culture and advances in application

CHANG Yan, WEI Wei   

  1. Institute of Clinical Pharmacology, AnhuiMedical University, theKey Laboratory of Antiinflammatory and Immunopharmacology, Ministry of Education, P.R.China, Hefei 230032, Anhui, China
  • Received:2009-06-17 Revised:2009-07-23 Online:2009-07-26 Published:2020-10-30

Abstract: The cell co-culture in vitro can simulate micro-environment in vivo and bridge the gap between monolayer cell culture and animal experiment. Thus, in many cases the experimental method is valuable in observing the interaction of cells and mechanisms and targets of drugs.This article reviews the cell co-culture and advances in application.The cell coculture can serve as a powerful tool for studying cell interaction and mechanisms of drugs.

Key words: co-culture, cell-culture, interaction

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