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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2005, Vol. 10 ›› Issue (7): 804-807.

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Therapeutic effects of Zhuyejiao tablets on chronic pelvic inflammation induced by coliform in rats

SUN Xiao-wei, CHENG Ti-juan1, LUO Hui-ying1, QIANG Yu-jing1, FANG Cai-xia1, ZHANG Wen-bin2   

  1. Department of Pathology, Basic Medical School, 1Department of Pharmacology, Pharmacy college, Lanzhou University, Lanzhou 730000, Gaosu, China;
    2Experimental center of science and technique Shanghai Traditional Medical and Medicine University, Shanghai 201203, China
  • Received:2005-05-31 Revised:2005-06-13 Online:2005-07-26 Published:2020-11-10

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Abstract: AIM: To investigate the therapeutic effects of Zhuyejiao tablets (Tab. ZYJ) on chronic pelvic inflammation (CPI) induced by coliform in rats. METHODS: The CPI model was made by injecting coliform OB4 standard strains in the uterus of rat. Animals were randomly divided into six groups and drugs were administered for 21 days, bid, respectively. The immune function of animals was measured and the uterus was pathologically observed. RESULTS: The level of serum agglutinin and lymphocyte transformation index markedly increased in all ZYJ groups. Morphological investigation also revealed the alleviation of inflammation in ZYJ groups. CONCLUTION: ZYJ has therapeutic effects on chronic pelvic inflammation in rats.

Key words: Zhuyejiao tablets, chronic pelvic inflammation, coliform O-B4, immune function, morphology

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