Abstract: Aim The effect of extract s of astralus(EA)on learning, memory andimmune function of C TX treated mice was observed.Methods The step-down test was adopted to investiga te learning and memory in mice;the method of enveloping CRBC was adopted to explorethe function of macrophage in abdominal cavity;3H-TdR marking method was used to observe the prolifernation of Tlymphocytes and the method of ELISA was applied to measurethe concentration of IFN-γin blood.Results EA (25 mg·kg^-1, 50 mg·kg^-1, ig, 21 d)could boost learning and memory, enhance the phagocytic activity of monocytes and the proli feration of Tlymphocytes of C TX treated mice, andincrease the concentration of IFN-γin blood of CTX treated mice.Conclusion EAnot only promote learning and memory, butregulate immune function.

Key words: extracts of astralus, cytoxan, memory, immune function