Abstract: Aim The immunopharmalogical roles of extract of Baoy uantang in mice with deficiency of vital function (DVF)were studied.Methods The mouse model with DVF was prepared by i.m administ ration of hydrocortisomum.Detection of phagocytosis and C3b receptor of macrophage was carried out with MT T method and YC roset teforming assay respectively.T cell transformation assay was car ried out with the method of MT T incorporation.The body weigh, idexes of spleen and thymus and WBC of the mice were determined by routine.Reaults The extract of Baoyuantang could block the decrease of body weight, WBC and the weight and index of thymus and spleen, and recover the function of T cells and macrophage in mice with DVF.Conclusion The extract of Baoyuantang had a supplementary treatmental effects on mice with DVF caused by hydrocortisonum.

Key words: Baoyuantang, animal model, macrophage, T lymphocyte, spleen, thymus