Abstract: AIM: To investigate the effects of Yanhong capsule on injury rats. METHODS: The changes of pathohistology were observed by local blood stasis on rats induced by hitting. The levels of blood rheology were detected. The rates of ear swelling induced by xylene were observed. The times of writhing induced by acetic acid were observed. RESULTS: Yanhong capsule could improve the symptoms of the surface congestion and edema on local blood stasis rats induced by hitting, recover the damage of muscle fiber, and reduce edema of the interstitial(P<0.05). Yanhong capsule could significantly reduce plasma viscosity, whole blood viscosity of high, medium, low shear rate(P<0.05), and significant improve indexes on blood rheological property. Yanhong capsule could reduce the rates of ear edema induced by xylene (P<0.05), and reduce the times of the writhing induced by acetic acid (P<0.05). CONCLUSION: Yanhong capsule has a great action on promotion blood circulation to dissipate, anti-inflammatory and painkillers.

Key words: Yanhong capsule, Injuries from impacts, Promotion blood circulation to dissipate, Pharmacodynamic study