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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2013, Vol. 18 ›› Issue (4): 455-460.

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Research advances in pharmacogenomics of levodopa

NING Wei, LIU Jie   

  1. Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University Xiangya School of Medicine, Changsha 410078,Hunan,China
  • Received:2012-10-24 Online:2013-04-26 Published:2013-04-26

Abstract: Levodopa is considered to be the 'gold standard' treatment for Parkinson's disease. This review aimed to summarize the influence of genetic polymorphisms on levodopa pharmacokinetics, pharmacodynamics and adverse reactions. In order to provide the basis for guide the clinical individualized medication of levodopa .

Key words: Levodopa, Genetic polymorphisms, Parkinson's disease

CLC Number: