Effect of acute hypervolemic hemodilution on postoperative cognitive function

Abstract

Abstract: Acute hypervolemic hemodilution(AHH) can effectively maintain hemodynamic stable and homeostasis,improve the perfusion of microcirculation,optimize hemorhcological condition,reduce the need for homologous blood transfusion and transfusion reactions.The pathogenesy of postoperative cognitive dysfunction(POCD) is complex,relates to the changes of multisystemic function,this article summarizes the effects of acute hypervolemic hemodilution on cerebral oxygenation metabolism,hemodynamics,pulmonary function,blood coagulation,immunological function etc,in order to expound the correlations between acute hypervolemic hemodilution and postoperative cognitive dyfunction.

Key words: acute hypervolemic hemodilution, cognitive function, blood conservation

CLC Number:

R614

SU Yong-jun, GUO Jian-rong, JIN Xiao-ju. Effect of acute hypervolemic hemodilution on postoperative cognitive function[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(11): 1316-1320.

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