Abstract: AIM: To observe the clinical effect of HuangqiJianzhong pill combined with omeprazole on gastric ulcer of deficiency cold of spleen and stomach type.METHODS: 100 cases gastric ulcer of deficiency cold of spleen and stomach type from our hospital were chose,who were randomly divided into two groups: the control group (omeprazole) and the experimental group (HuangqiJianzhong pill and omeprazole),treatment lasted for 4 weeks.RESULTS: 20 cases in the control group were fully recovered, remarkably effective:15 cases, the total effective rate was 70%;30 cases in the experimental group were fully recovered, remarkably effective:17 cases, the total effective rate was 94%,there was statistically significant difference (P<0.05). Compared with the control group,the main symptoms of gastric ulcer in the experimental group were significantly reduced, there was statistically significant difference (P<0.05). The rate of Hp clearance was 78% and 56% in the control group and the experimental group,there was statistically significant difference (P<0.05).CONCLUSION: The effect using HuangqiJianzhong pill combined with omeprazole for the treatment gastric ulcer of deficiency cold of spleen and stomach type is better than omeprazole alone.

Key words: gastric ulcer of deficiency cold of spleen and stomach type, huangqijianzhong pill, omeprazole