关键词: 孤独症谱系障碍, 患病率, 影响因素, 学前儿童

Abstract: Objective To investigate the epidemic and related factors of autism spectrum disorders (ASD) in preschool children of Zaozhuang city.Methods Radom cluster sampling method was used to select 8 000 children aged 2~6 years old from 5 regions in Zaozhuang city.Clancy Autism Behavior Scale (CABS) and a self-designed questionnaire were used to conduct cross-sectional investigation among the children and their parents. Reaults The positive rate of ASD was 6.63‰,the positive rates in boys was 5.43‰,the positive rates in girls was 1.21‰.The proportion of maternal and paternal age,maternal emotion during in the pregnant time and the disease of perinatal stage in ASD group were higher than those in the normal group.The logistic analysis showed the protective factors of ASD included good maternal emotion and lower maternal age.The higher father paternal age,father introverted,neonatal asphyria and meonatal jaundice were risk factors of ASD.Conclusions The prevalence of ASD in preschool children in Zaozhuang is similar to that of other city.Logistic analysis showed maternal health care during pregnancy has important significance for guiding,and grasping the best child-bearing age could decrease the risk of ASD.

Key words: autism spectrum disorder, prevalence, influence factors, preschool children