中国儿童保健杂志 ›› 2018, Vol. 26 ›› Issue (10): 1096-1099.DOI: 10.11852/zgetbjzz2018-26-10-14

• 综述与讲座 • 上一篇    下一篇

儿童注意缺陷多动障碍药物依从性及影响因素

赵秋霞, 陈立   

  1. 重庆医科大学附属儿童医院儿童青少年生长发育与心理健康中心;儿童发育疾病研究教育部重点实验室,重庆 400014
  • 收稿日期:2018-04-19 发布日期:2018-10-10 出版日期:2018-10-10
  • 通讯作者: 陈立,E-mail:chenli2012@126.com
  • 作者简介:赵秋霞(1991-),女,云南人,住院医师,硕士研究生,主要研究方向为注意缺陷多动障碍。
  • 基金资助:
    重庆市高等教育学会2015-2016年度高等教育科学研究课题(CQGJ153583B);重庆医科大学附属儿童医院转化医学项目(zhyx2012-2)

Status and influencing factors of medication compliance in children with attention deficit hyperactivity disorder

ZHAO Qiu-xia, CHEN Li   

  1. Division of Children and Adolescents Growth and Development & Mental Health,Children′s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing 400014,China
  • Received:2018-04-19 Online:2018-10-10 Published:2018-10-10
  • Contact: CHEN Li,E-mail:chenli2012@126.com

摘要: 注意缺陷多动障碍(ADHD)是儿童和青少年期最常见的神经发育障碍,约影响全世界5%~11%的儿童。药物治疗是6岁以上ADHD儿童首选方案,约70%患者药物治疗有效。多种药物已被应用于ADHD临床治疗,如盐酸哌甲酯和苯丙胺、盐酸托莫西汀及可乐定和胍法辛等。药物副作用、药物剂型、患儿生长速度、家庭因素、患儿用药体验、睡眠问题或障碍等多种因素均会影响药物依从性。医生、父母和患儿共享信息、商讨治疗方案、监测疗效和副作用,并积极开展医教结合、家校结合,实施行为管理和干预,有助于提高依从性、改善治疗效果,促进患儿学业成绩及社会功能、生活质量全面提升。

关键词: 注意缺陷多动障碍, 药物治疗, 依从性, 影响因素

Abstract: Attention deficit hyperactivity disorder (ADHD) is the most common neuro-developmental disorder,which affects 5%~11% children around the world.Medication therapy is the preferred treatment for children aged over 6 years old with ADHD.It is considered that medication is effective for 70% of ADHD children.A variety of drugs have been used,such as methylphenidate and amphetamine,atomoxetine,guanfacine and clonidine.Medication adherence can be influenced by many factors,such as side effects of drugs,dosage form,growth velocity,families,and patients′ experience of taking medication,as well as sleep disorders.Doctors,parents and children cooperate to share information,decide on the medication treatment plan,monitor the effect of drug treatment and side effects,and actively carry out the combination of medical education and home school to implement behavior management and intervention,which will significantly improve the compliance,improve the treatment effect of medication treatment,promote the study of children with ADHD,improve overall promotion of social function and quality of life.

Key words: attention deficit hyperactivity disorder, pharmacotherapy, medication compliance, influencing factors

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