肥胖儿童心血管代谢风险相关的预警指标研究进展

doi:10.11852/zgetbjzz2020-1285

中国儿童保健杂志 ›› 2021, Vol. 29 ›› Issue (11): 1208-1212.DOI: 10.11852/zgetbjzz2020-1285

肥胖儿童心血管代谢风险相关的预警指标研究进展

韩琰, 彭璐婷, 李晓南

南京医科大学附属儿童医院儿童保健科,江苏南京 210008

收稿日期:2020-07-04 修回日期:2020-09-08 发布日期:2021-11-05 出版日期:2021-11-10
通讯作者: 李晓南,E-mail:xiaonan6189@163.com
作者简介:韩琰(1996-),女,江苏人,在读硕士研究生,主要从事儿童保健的临床研究。
基金资助:
国家自然科学基金(81773421);江苏省重点病种规范化诊疗项目(BE2015607);江苏省科教强卫工程医学创新团队(CXTDA2017035)

Research progress on the indicators of cardiometabolic risk in obese children

HAN Yan, PENG Lu-ting, LI Xiao-nan

Department of Child Health Care,Children′s Hospital of Nanjing Medical University,Nanjing,Jiangsu 210008,China

Received:2020-07-04 Revised:2020-09-08 Online:2021-11-10 Published:2021-11-05
Contact: LI Xiao-nan,E-mail:xiaonan6189@163.com

摘要/Abstract

摘要： 儿童期肥胖增加血脂异常、高血压、高血糖等心血管代谢风险(CMR),并可持续至成人,使代谢性疾病低龄化。近年发现,尿酸、视黄醇结合蛋白4、维生素D、颈围等与肥胖儿童CMR密切相关,可作为CMR的预警指标,为心血管代谢疾病的早期防治提供新靶标。认识预警指标与代谢风险的关系、作用机制和临床意义,有助于早期识别有CMR相关因素的高危人群并进行干预。

关键词: 儿童肥胖, 心血管代谢风险, 尿酸, 视黄醇结合蛋白4, 维生素D, 颈围

Abstract: Childhood obesity increases the cardiometabolic risks (CMR) such as dyslipidemia,hypertension,and hyperglycemia,and usually persists into adulthood,leading to younger age trend of metabolic diseases. At present,a large number of studies have found that uric acid,retinol-binding protein 4,vitamin D and other factors are related to the CMR in obese children,which can be used as a marker of CMR and provide new ideas for the prevention and treatment of cardiovascular metabolic diseases. Therefore,it is of great importance to understand the relationship and mechanism between indicators and CMR,which is beneficial for early identification and intervention of high-risk groups of cardiovascular and metabolic diseases.

Key words: childhood obesity, cardiometabolic risk, uric acid, retinol-binding protein 4, vitamin D, neck circumference

中图分类号:

R723.14

韩琰, 彭璐婷, 李晓南. 肥胖儿童心血管代谢风险相关的预警指标研究进展[J]. 中国儿童保健杂志, 2021, 29(11): 1208-1212.

HAN Yan, PENG Lu-ting, LI Xiao-nan. Research progress on the indicators of cardiometabolic risk in obese children[J]. Chinese Journal of Child Health Care, 2021, 29(11): 1208-1212.

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肥胖儿童心血管代谢风险相关的预警指标研究进展

Research progress on the indicators of cardiometabolic risk in obese children

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