Abstract: Objective To understand the incidence rate and influential factors of wheezing among infants aged 6 to 24 months in Enshi,China,and to provide evidences for wheezing prevention. Methods A total of 1 724 infants were recruited using multi-stage stratified cluster sampling,and informations including demographic characteristics,family condition,in utero exposure,nursing behavior and wheezing information were collected by questionnaire survey.Multivariate Logistic regression was performed to analyze associated factors with wheezing. Results Among 1 724 infants,897 (52%) were boys and 827(48%) were girls,and the average age was (14.6±5.4) months.The incidence rate of wheezing was 1.97%,2.56% for boys and 1.33% for girls respectively.Multivariate Logistic regression analysis showed wheezing was associated with food allergy history and in utero exposure to second-hand tobacco. Conclusion Infants who had food allergy history and in utero exposure to second-hand tobacco have higher risk of wheezing.

Key words: infants, wheeze, incidence rate, influential factors

摘要： 目的 了解恩施州6~24月龄婴幼儿喘息发病情况及其影响因素,为婴幼儿喘息的预防提供依据。方法 采取多阶段分层整群抽样的方法,抽取1 724名婴幼儿,使用问卷调查收集婴幼儿的一般情况、家庭情况、母亲孕期状况、看护行为和喘息情况。多因素Logistic回归分析用于探索婴幼儿喘息的影响因素。结果 接受调查的婴幼儿中,男女分别为897人(52.0%)和827人(48.0%),平均月龄为(14.6±5.4)个月。喘息的发生率为1.97%,男女发生率分别为2.56%和1.33%。Logistic回归分析结果显示有食物过敏史和母亲孕期有二手烟暴露是婴幼儿喘息的危险因素。结论 恩施州6~24月龄婴幼儿中,食物过敏史及母亲孕期有二手烟暴露史是喘息发生的危险因素。

关键词: 婴幼儿, 喘息, 发生率, 影响因素